Slot is Disabled on some B560 Motherboards with 10th

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On newer processors both the first x16 and first NVMe x4 slot both come off the processor The block diagram for your motherboard is going to be

motherboard m2 slot Your notebook has support for SATA-3 SSD drives with TLC memory type NVMe types are not suported Examples are at Newegg

100 joker staxx slot 2 slots — supporting both PCIe and — that allow you to expand your system with high-performance SSD storage Designed for the latest generation of NVMe